Teacher Details

Shilpy Sharma

Department of Biotechnology

shilpy.sharma@gmail.com

Research Areas : Disease Epigenetics, DNA repair, Diabetes


Google Scholar Profile | ResearchGate Profile

1)    Pawar, S.S., Ketkar, R.N., Gaware, P.B., Jagushte, K.U., Dhawne, D., Save, S.N., Sharma, S., Periyasamy, G., Chimthanwala, N.M., Sathaye, S., Joshi, S.V. (2024). Molybdenum-maltolate as a Molybdopterin mimic for bioinspired oxidation reaction. Dalton Transactions, ISSN(print/online): 1477-9226/1477-9234, URL/DOI: http://dx.doi.org/10.1039/D3DT04296K
2)    Yousf, S., Batra, H.S., Jha, R.M., Sardesai, D.M., Ananthamohan, K., Chugh, J., Sharma, S. (2024). Identification of potential serum biomarkers associated with HbA1c levels in Indian type 2 diabetic subjects using NMR-based metabolomics. Clinica Chimica Acta, 557, 117857. ISSN(print/online): 0009-8981/1873-3492, URL/DOI: http://dx.doi.org/10.1016/j.cca.2024.117857
3)    Yadav, S.S., Roham, P.H., Roy, S., Sharma, S. (2023). Connecting islet-specific hub genes and pathways in type 2 diabetes mellitus through the bioinformatics lens. Human Gene, 36, 201177. ISSN(print/online): 2773-0441, URL/DOI: http://dx.doi.org/10.1016/j.humgen.2023.201177
4)    Mondal, A., Save, S.N., Sarkar, S., Mondal, D., Mondal, J., Sharma, S., Talukdar, P. (2023). A Benzohydrazide-Based Artificial Ion Channel that Modulates Chloride Ion Concentration in Cancer Cells and Induces Apoptosis by Disruption of Autophagy. Journal of the American Chemical Society, 145 (17), 9737–9745. ISSN(print/online): 0002-7863/1520-5126, URL/DOI: http://dx.doi.org/10.1021/jacs.3c01451
5)    Roham, P.H., Kamath, J.J., Sharma, S. (2023). Dissecting the Interrelationship between COVID-19 and Diabetes Mellitus. Advanced Biology, 7 (8), e2300107. ISSN(print/online): 2701-0198, URL/DOI: http://dx.doi.org/10.1002/adbi.202300107
6)    Yousf, S., Malla, J.A., Sardesai, D.M., Sharma, S., Talukdar, P., Chugh, J. (2023). Mapping metabolic perturbations induced by glutathione activatable synthetic ion channels in human breast cancer cells. Journal of Pharmaceutical and Biomedical Analysis, 235, 115605. ISSN(print/online): 0731-7085/1873-264X, URL/DOI: http://dx.doi.org/10.1016/j.jpba.2023.115605
7)    Roy, N.J., Save, S.N., Sharma, V., Abraham, B., Kuttanamkuzhi, A., Sharma, S., Lahiri, M., Talukdar, P. (2023). NAD(P)H:Quinone Acceptor Oxidoreductase 1 (NQO1) Activatable Salicylamide H+/Cl− Transporters. Chemistry-A European Journal, 29 (51), e202301412. ISSN(print/online): 0947-6539/1521-3765, URL/DOI: http://dx.doi.org/10.1002/chem.202301412
8)    Singh, S., Ghosh, P., Sharma, S., Bhargava, S., Kumar, A.R. (2023). Tetrahydropalmatine from medicinal plants activates human glucokinase to regulate glucose homeostasis. Biotechnology and Applied Biochemistry, ISSN(print/online): 0885-4513/1470-8744, URL/DOI: http://dx.doi.org/10.1002/bab.2541
9)    Malla, J.A., Upadhyay, A., Ghosh, P., Mondal, D., Mondal, A., Sharma, S., Talukdar, P. (2022). Chloride Transport across Liposomes and Cells by Nontoxic 3-(1 H-1,2,3-Triazol-1-yl)benzamides. Organic Letters, 24 (23), 4124-4128. ISSN(print/online): 1523-7060/1523-7052, URL/DOI: http://dx.doi.org/10.1021/acs.orglett.2c01219
10)    Roham, P.H., Save, S.N., Sharma, S. (2022). Human islet amyloid polypeptide: A therapeutic target for the management of type 2 diabetes mellitus. Journal of Pharmaceutical Analysis, 12 (4), 556-569. ISSN(print/online): 2095-1779, URL/DOI: http://dx.doi.org/10.1016/j.jpha.2022.04.001
11)    Bishoyi, A.K., Roham, P.H., Rachineni, K., Save, S., Hazari, M.A., Sharma, S., Kumar, A. (2021). Human islet amyloid polypeptide (hIAPP)–a curse in type II diabetes mellitus: insights from structure and toxicity studies. Biological Chemistry, 402 (2), 133-153. ISSN(print/online): 1431-6730/1437-4315, URL/DOI: http://dx.doi.org/10.1515/hsz-2020-0174
12)    Dubey, R., Kulkarni, S.H., Dantu, S.C., Panigrahi, R., Sardesai, D.M., Malik, N., Acharya, J.D., Chugh, J., Sharma, S., Kumar, A. (2021). Myricetin protects pancreatic beta-cells from human islet amyloid polypeptide (hIAPP) induced cytotoxicity and restores islet function. Biological Chemistry, 402 (2), 179-194. ISSN(print/online): 1431-6730/1437-4315, URL/DOI: http://dx.doi.org/10.1515/hsz-2020-0176
13)    Mondal, A., Malla, J.A., Paithankar, H., Sharma, S., Chugh, J., Talukdar, P. (2021). A Pyridyl-Linked Benzimidazolyl Tautomer Facilitates Prodigious H+/Cl– Symport through a Cooperative Protonation and Chloride Ion Recognition. Organic Letters, 23 (15), 6131-6136. ISSN(print/online): 1523-7060/1523-7052, URL/DOI: http://dx.doi.org/10.1021/acs.orglett.1c02235
14)    Guleria, A., Poluri, K.M., Kumar, S., Tiwari, D.K., Singh, S.K., Sharma, S., Kumar, D. (2021). Recommendations of National symposium on “Integrative Medicines and Health: From Basic to Translational Research”. Annals of Ayurvedic Medicine, 10 (1), 74-76. ISSN(print/online): 2277-4092/2347-6923, URL/DOI: https://www.ejmanager.com/mnstemps/70/70-1608012814.pdf?t=1663926211
15)    Malla, J.A., Umesh, R.M., Yousf, S., Mane, S., Sharma, S., Lahiri, M., Talukdar, P. (2020). A Glutathione Activatable Ion Channel Induces Apoptosis in Cancer Cells by Depleting Intracellular Glutathione Levels. Angewandte Chemie, 59 (20), 7944-7952. ISSN(print/online): 1433-7851/1521-3773, URL/DOI: http://dx.doi.org/10.1002/anie.202000961
16)    Datir, S.S., Yousf, S., Sharma, S., Kochle, M., Ravikumar, A., Chugh, J. (2020). Cold storage reveals distinct metabolic perturbations in processing and non-processing cultivars of potato (Solanum tuberosum L.). Scientific Reports, 10 (1), 6268. ISSN(print/online): 2045-2322, URL/DOI: http://dx.doi.org/10.1038/s41598-020-63329-5
17)    Dubey, R., Patil, K., Dantu, S.C., Sardesai, D.M., Bhatia, P., Malik, N., Acharya, J.D., Sarkar, S., Ghosh, S., Chakrabarti, R., Sharma, S., Kumar, A. (2019). Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic β-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity. Biochemical Journal, 476 (5), 889-907. ISSN(print/online): 0264-6021/1470-8728, URL/DOI: http://dx.doi.org/10.1042/BCJ20180820
18)    Yousf, S., Sardesai, D.M., Mathew, A.B., Khandelwal, R., Acharya, J.D., Sharma, S., Chugh, J. (2019). Metabolic signatures suggest o-phosphocholine to UDP-N-acetylglucosamine ratio as a potential biomarker for high-glucose and/or palmitate exposure in pancreatic β-cells. Metabolomics, 15 (4), 55. Google Scholar Citations, ISSN(print/online): 1573-3882/1573-3890, URL/DOI: http://dx.doi.org/10.1007/s11306-019-1516-3
19)    Paithankar, H., Jadhav, P.V., Naglekar, A.S., Sharma, S., Chugh, J. (2018). 1 H, 13 C and 15 N resonance assignment of domain 1 of trans-activation response element (TAR) RNA binding protein isoform 1 (TRBP2) and its comparison with that of isoform 2 (TRBP1). Biomolecular NMR Assignments, 12 (1), 189-194. ISSN(print/online): 1874-2718/1874-270X, URL/DOI: http://dx.doi.org/10.1007/s12104-018-9807-6
20)    Dubey, R., Minj, P., Malik, N., Sardesai, D.M., Kulkarni, S.H., Acharya, J.D., Bhavesh, N.S., Sharma, S., Kumar, A. (2017). Recombinant human islet amyloid polypeptide forms shorter fibrils and mediates β-cell apoptosis via generation of oxidative stress. Biochemical Journal, 474 (23), 3915-3934. ISSN(print/online): 0264-6021/1470-8728, URL/DOI: http://dx.doi.org/10.1042/BCJ20170323
21)    Rajendra, R., Bhatia, P., Justin, A., Sharma, S., Ballav, N. (2015). Homogeneously-alloyed gold–silver nanoparticles as per feeding moles. Journal of Physical Chemistry C, 119 (10), 5604-13. Google Scholar Citations, ISSN(print/online): 1932-7447/1932-7455, URL/DOI: http://dx.doi.org/10.1021/jp512528j
22)    Bhatia, P., Raina, S., Chugh, J., Sharma, S. (2015). miRNAs: early prognostic biomarkers for Type 2 diabetes mellitus?. Biomarkers in Medicine, 9 (10), 1025-1040. Google Scholar Citations, ISSN(print/online): 1752-0363/1752-0371, URL/DOI: http://dx.doi.org/10.2217/bmm.15.69
23)    Watanabe, S., Pinto, J.M., Bashir, M.E.H., De Tineo, M., Suzaki, H., Baroody, F.M., Naclerio, R.M., Sharma, S. (2014). Effect of Prednisone on Nasal Symptoms and Peripheral Blood T-cell Function in Chronic Rhinosinusitis. International Forum of Allergy and Rhinology, 4 (8), 609-616 . ISSN(print/online): 2042-6976/2042-6984, URL/DOI: http://dx.doi.org/10.1002/alr.21336
24)    Sharma, S., Helchowski, C.M., Canman, C.E. (2013). The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 743, 97-110. Google Scholar Citations, ISSN(print/online): 0027-5107/1873-135X, URL/DOI: http://dx.doi.org/10.1016/j.mrfmmm.2012.11.002
25)    Tian, F., Sharma, S., Zou, J., Lin, S.Y., Wang, B., Rezvani, K., Wang, H., Parvin, J.D., Ludwig, T., Canman, C.E., Zhang, D. (2013). BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade. Proceedings of the National Academy of Sciences of the United States of America, 110 (33), 13558-13563. Google Scholar Citations, ISSN(print/online): 1091-6490, URL/DOI: http://dx.doi.org/10.1073/pnas.1306534110
26)    Kumar, A., Sharma, S., Agrawal, A., Ghosh, B. (2012). Association of the-1072G/A Polymorphism in the LTC4S Gene with Asthma in an Indian Population. International Archives of Allergy and Immunology, 159 (3), 271-277. Google Scholar Citations, ISSN(print/online): 1018-2438/1423-0097, URL/DOI: http://dx.doi.org/10.1159/000336675
27)    Sharma, S., Watanabe, S., Sivam, A., Wang, J., Neuwirth, S.J., Perez, R.I., De Tineo, M., Baroody, F.M., Naclerio, R.M., Pinto, J.M. (2012). Peripheral blood and tissue T regulatory cells in chronic rhinosinusitis. American Journal of Rhinology and Allergy, 26 (5), 371-9. Google Scholar Citations, ISSN(print/online): 1945-8924/1945-8932, URL/DOI: http://dx.doi.org/10.2500/ajra.2012.26.3800
28)    Sharma, S., Canman, C.E. (2012). REV1 and DNA polymerase zeta in DNA interstrand crosslink repair. Environmental and Molecular Mutagenesis, 53 (9), 725-740. Google Scholar Citations, ISSN(print/online): 0893-6692/1098-2280, URL/DOI: http://dx.doi.org/10.1002/em.21736
29)    Sharma, S., Hicks, J.K., Chute, C.L., Brennan, J.R., Ahn, J.Y., Glover, T.W., Canman, C.E. (2012). REV1 and polymerase ζ facilitate homologous recombination repair. Nucleic Acids Research, 40 (2), 682-691. Google Scholar Citations, ISSN(print/online): 0305-1048/1362-4962, URL/DOI: http://dx.doi.org/10.1093/nar/gkr769
30)    Sharma, S., Shah, N.A., Joiner, A.M., Roberts, K.H., Canman, C.E. (2012). DNA polymerase zeta is a major determinant of resistance to platinum-based chemotherapeutic agents. Molecular Pharmacology, 81 (6), 778-787. Google Scholar Citations, ISSN(print/online): 0026-895X/1521-0111, URL/DOI: http://dx.doi.org/10.1124/mol.111.076828
31)    Sharma, S., Vasnani, R., De Tineo, M., Du, G., Pinto, J.M., Baroody, F.M., Naclerio, R.M. (2011). Recruitment factors which affect the outcome of a seasonal allergic rhinitis trial. Allergy and Asthma Proceedings, 32 (1), 55-63. Google Scholar Citations, ISSN(print/online): 1088-5412/1539-6304, URL/DOI: http://dx.doi.org/10.2500/aap.2011.32.3414
32)    Esteitie, R., Emani, J., Sharma, S., Suskind, D.L., Baroody, F.M. (2011). Effect of fluticasone furoate on Interleukin 6 secretion from adenoid tissues in children with obstructive sleep apnea. JAMA Otolaryngology-Head & Neck Surgery, 137 (6), 576-582. Google Scholar Citations, ISSN(print/online): 2168-6181/2168-619X, URL/DOI: http://dx.doi.org/10.1001/archoto.2011.86
  

Publications Before 2011


33)    Sharma, S., Rathored, J., Ghosh, B., Sharma, S.K. (2010). Genetic polymorphisms in TNF genes and tuberculosis in North Indians. BMC Infectious Diseases, 10 (1), 165. Google Scholar Citations, ISSN(print/online): 1471-2334, URL/DOI: http://dx.doi.org/10.1186/1471-2334-10-165
34)    Kumar, D., Misra, J.R., Kumar, A., Chugh, J., Sharma, S., Hosur, R.V. (2009). NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3). Proteins: Structure, Function and Bioinformatics, 75 (4), 1046-1050. Google Scholar Citations, ISSN(print/online): 0887-3585/1097-0134, URL/DOI: http://dx.doi.org/10.1002/prot.22389