Teacher Details

Manali Sushrut Joshi

Bioinformatics Centre

manalijoshi@unipune.ac.in


Google Scholar Profile |

1)    Anjulal, H., Saha, A., Barvkar, V.T., Pawar, H., Joshi, M., Zinjarde, S.S. (2026). Overexpression, biochemical characterization, and structural modeling of polyhydroxybutyrate depolymerase from Nocardiopsis dassonvillei. Enzyme and Microbial Technology, 193, 110767. ISSN(print/online): 0141-0229/1879-0909, URL/DOI: http://dx.doi.org/10.1016/j.enzmictec.2025.110767
2)    Gotkhindikar, A., Chakravorty, D., Sengupta, D., Joshi, M., Assmann, S.M. (2025). Is GCR1 the GPR157 of plants?. Plant Physiology, 197 (2), 057. ISSN(print/online): 0032-0889/1532-2548, URL/DOI: http://dx.doi.org/10.1093/plphys/kiaf057
3)    Mahajan, P., Gor, H. R., Jadhav, S., Joshi, M., Nema, V. (2025). Host-Directed Therapeutic for the treatment of Mycobacterium tuberculosis. Microbiological Research, 299, 128253. ISSN(print/online): 0944-5013/1618-0623, URL/DOI: http://dx.doi.org/10.1016/j.micres.2025.128253
4)    Suneesh, N.S., Dhotre, K., Mahajan, P., Dass, D., Banerjee, A., Siddiqi, N.J., Malik, A., Joshi, M., Khan, A.A., Nema, V., Mukherjee, A. (2025). Reverse vaccinology-based design of multivalent multiepitope mRNA vaccines targeting key viral proteins of Herpes Simplex Virus type-2. Frontiers in Immunology, 16, 1586271. Google Scholar Citations, ISSN(print/online): 1664-3224, URL/DOI: http://dx.doi.org/10.3389/fimmu.2025.1586271
5)    Mahajan, M., Ghodke, G., Joshi, M., Chaudhary, A., Kaul-Ghanekar, R. (2025). Matairesinol Targets Lipid Metabolism Reprogramming in AR-Independent Prostate Cancer Cells. Asian Pacific Journal of Cancer Prevention, 26 (8), 2855-2867. ISSN(print/online): 1513-7368/2476-762X, URL/DOI: http://dx.doi.org/10.31557/APJCP.2025.26.8.2855
6)    Mahajan, P., Gor, H., Joshi, M., Nema, V. (2025). DapB is a conserved target for tackling antimicrobial resistance in Mycobacterium tuberculosis. Journal of Biomolecular Structure and Dynamics, ISSN(print/online): 0739-1102/1538-0254, URL/DOI: http://dx.doi.org/10.1080/07391102.2025.2581074
7)    Nikte, S.V., Joshi, M., Sengupta, D. (2024). State-dependent dynamics of extramembrane domains in the β2-adrenergic receptor. Proteins: Structure, Function and Bioinformatics, 92 (3), 1-12. ISSN(print/online): 0887-3585/1097-0134, URL/DOI: http://dx.doi.org/10.1002/prot.26613
8)    Rajan, B. R. S., Joshi, M., Tillu, G. (2024). Unlocking ancient wisdom with technology – A special issue on Ayurveda and technology. Journal of Ayurveda and Integrative Medicine, 15 (3), 101020. ISSN(print/online): 0975-9476/0976-2809, URL/DOI: http://dx.doi.org/10.1016/j.jaim.2024.101020
9)    Joshi, M.S., Lin, S.J., Vona, B., Lau, T., Huang, K., Zaki, M.S., Aldeen, H.S., Karimiani, E.G., Rocca, C., Noureldeen, M.M., Saad, A.K., Petree, C....ed. (2023). Evaluating the association of biallelic OGDHL variants with significant phenotypic heterogeneity. . Genome Medicine, 15 (1), 102. ISSN(print/online): 1756-994X, URL/DOI: http://dx.doi.org/10.1186/s13073-023-01258-4
10)    Paithankar, H., Tarang, G.S., Parvez, F., Marathe, A., Joshi, M., Chugh, J. (2022). Inherent conformational plasticity in dsRBDs enables interaction with topologically distinct RNAs. Biophysical Journal, 121 (6), 1038-1055. ISSN(print/online): 0006-3495/1542-0086, URL/DOI: http://dx.doi.org/10.1016/j.bpj.2022.02.005
11)    Gujar, N., Nikte, S.V., Joshi, R.S., Joshi, M. (2021). Molecular Characterization of the β2-like Octopamine Receptor of Helicoverpa armigera. Journal of Membrane Biology, 254, 311-319. ISSN(print/online): 0022-2631/1432-1424, URL/DOI: http://dx.doi.org/10.1007/s00232-021-00172-3
12)    Alai, S., Gujar, N., Joshi, M., Gautam, M., Gairola, S. (2021). Pan-India novel coronavirus SARS-CoV-2 genomics and global diversity analysis in spike protein. Heliyon, 7 (3), e06564. ISSN(print/online): 2405-8440, URL/DOI: http://dx.doi.org/10.1016/j.heliyon.2021.e06564
13)    Borse, S., Joshi, M., Saggam, A., Bhat, V., Walia, S., Marathe, A., Sagar, S., Chavan-Gautam, P., Girme, A., Hingorani, L., Tillu, G. (2021). Ayurveda botanicals in COVID-19 management: An in silico multi-target approach. PloS One, 16 (6), e0248479. Google Scholar Citations, ISSN(print/online): 1932-6203, URL/DOI: http://dx.doi.org/10.1371/journal.pone.0248479
14)    Kharche, S., Joshi, M., Chattopadhyay, A., Sengupta, D. (2021). Conformational plasticity and dynamic interactions of the N-terminal domain of the chemokine receptor CXCR1. PLoS Computational Biology, 17 (5), e1008593. Google Scholar Citations, ISSN(print/online): 1553-7358/1553-734X, URL/DOI: http://dx.doi.org/10.1371/journal.pcbi.1008593
15)    Nikte, S.V., Sonar, K., Tandale, A., Joshi, M., Sengupta, D. (2021). Loss of a water-mediated network results in reduced agonist affinity in a β2-adrenergic receptor clinical variant. Biochimica et Biophysica Acta- Proteins and Proteomics, 1869 (4), 140605. ISSN(print/online): 1570-9639/1878-1454, URL/DOI: http://dx.doi.org/10.1016/j.bbapap.2021.140605
16)    Joshi, M., Lin, S.J., Vona, B., Barbalho, P.G., Kaiyrzhanov, R., Maroofian, R., Petree, C., Severino, M., Stanley, V., Varshney, P., Bahena, P., Alzahrani, F. (2021). Biallelic variants in KARS1 are associated with neurodevelopmental disorders and hearing loss recapitulated by the knockout zebrafish. Genetics in Medicine, 23 (10), 1933-1943. ISSN(print/online): 1098-3600/1530-0366, URL/DOI: http://dx.doi.org/10.1038/s41436-021-01239-1
17)    Kulkarni, A.S., Ramesh, R., Walia, S., Sayyad, S.I., Gathalkar, G.B., Balamkundu, S., Joshi, M., Sen, A., Reddy, D.S. (2021). Identification of a Novel Series of Potent Organosilicon Mosquito Repellents. ACS Omega, 6 (46), 31236-31243. ISSN(print/online): 2470-1343, URL/DOI: http://dx.doi.org/10.1021/acsomega.1c04961
18)    Nikte, S., Gahankari, A., Mulla, J., Sengupta, D., Joshi, M., Tamhane, V. (2020). In vitro and in silico studies on membrane interactions of diverse Capsicum annuum flower γ-thionin peptides. Proteins: Structure, Function and Bioinformatics, 88 (1), 227-236. ISSN(print/online): 0887-3585/1097-0134, URL/DOI: http://dx.doi.org/10.1002/prot.25791
19)    Kumari, J., Bendre, A.D., Bhosale, S., Vinnakota, R., Burada, A.P., Ravelli, R., Peters, P.J., Joshi, M., Kumar, J. (2020). Structural dynamics of the GluK3-kainate receptor neurotransmitter binding domains revealed by cryo-EM. International Journal of Biological Macromolecules, 149, 1051-1058. ISSN(print/online): 0141-8130/1879-0003, URL/DOI: http://dx.doi.org/10.1016/j.ijbiomac.2020.01.282
20)    Jamalpure, S., Panditrao, G., Kulabhusan, P.K., Hameed, A.S., Paknikar, K.M., Joshi, M., Rajwade, J.M. (2020). In silico studies on the interaction of phage displayed biorecognition element (TFQAFDLSPFPS) with the structural protein VP28 of white spot syndrome virus. Journal of Molecular Modeling, 26 (10), 264. ISSN(print/online): 1610-2940/0948-5023, URL/DOI: http://dx.doi.org/10.1007/s00894-020-04524-z
21)    Palrecha, S., Lakade, D., Kulkarni, A., Pal, J.K., Joshi, M. (2019). Computational insights into the interaction of small molecule inhibitors with HRI kinase domain. Journal of Biomolecular Structure and Dynamics, 37 (7), 1715-1723. Google Scholar Citations, ISSN(print/online): 0739-1102/1538-0254, URL/DOI: http://dx.doi.org/10.1080/07391102.2018.1465850
22)    Bhosale, S., Nikte, S.V., Sengupta, D., Joshi, M. (2019). Differential Dynamics Underlying the Gln27Glu Population Variant of the β2-Adrenergic. Journal of Membrane Biology, 252, 499–507. Google Scholar Citations, ISSN(print/online): 0022-2631/1432-1424, URL/DOI: http://dx.doi.org/10.1007/s00232-019-00093-2
23)    Kharche, S., Joshi, M., Sengupta, D., Chattopadhyay, A. (2018). Membrane-induced organization and dynamics of the N-terminal domain of chemokine receptor CXCR1: insights from atomistic simulations. Chemistry and Physics of Lipids, 210, 142-148. ISSN(print/online): 0009-3084/1873-2941, URL/DOI: http://dx.doi.org/10.1016/j.chemphyslip.2017.09.003
24)    Barage, S., Kulkarni, A., Pal, J.K., Joshi, M. (2017). Unravelling the structural interactions between PKR kinase domain and its small molecule inhibitors using computational approaches. Journal of Molecular Graphics and Modelling, 75, 322-329. ISSN(print/online): 1093-3263/1873-4243, URL/DOI: http://dx.doi.org/10.1016/j.jmgm.2017.06.009
25)    Tandale, A., Joshi, M., Sengupta, D. (2016). Structural insights and functional implications of inter-individual variability in beta(2)-adrenergic receptor. Scientific Reports, 6, 24379. Google Scholar Citations, ISSN(print/online): 2045-2322, URL/DOI: http://dx.doi.org/10.1038/srep24379
26)    Agrawal, S., Kulabhusan, P.K., Joshi, M., Bodas, D., Paknikar, K.M. (2016). A high affinity phage-displayed peptide as a recognition probe for the detection of Salmonella Typhimurium. Journal of Biotechnology, 231, 40-45. Google Scholar Citations, ISSN(print/online): 0168-1656/1873-4863, URL/DOI: http://dx.doi.org/10.1016/j.jbiotec.2016.05.027
27)    Joshi, M., Rajpathak, S.N., Narwade, S.C., Deobagkar, D. (2016). Ensemble-Based Virtual Screening and Experimental Validation of Inhibitors Targeting a Novel Site of Human DNMT1. Chemical Biology and Drug Design, 88 (1), 5-16. Google Scholar Citations, ISSN(print/online): 1747-0277/1747-0285, URL/DOI: http://dx.doi.org/10.1111/cbdd.12741
28)    Shahane, G., Parsania, C., Sengupta, D., Joshi, M. (2014). Molecular insights into the dynamics of pharmacogenetically important N-terminal variants of the human β2-adrenergic receptor. PLoS Computational Biology, 10 (12), e1004006. Google Scholar Citations, ISSN(print/online): 1553-7358/1553-734X, URL/DOI: http://dx.doi.org/10.1371/journal.pcbi.1004006
29)    Joshi, M., Kulkarni, A., Pal, J.K. (2013). Small molecule modulators of eukaryotic initiation factor 2α kinases, the key regulators of protein synthesis. Biochimie, 95 (11), 1980-1990. Google Scholar Citations, ISSN(print/online): 0300-9084/1638-6183, URL/DOI: http://dx.doi.org/10.1016/j.biochi.2013.07.030
30)    Mallipeddi, P.L., Joshi, M.S., Briggs, J.M. (2012). Pharmacophore-based virtual screening to aid in the identification of unknown protein function. Chemical Biology and Drug Design, 80 (6), 828-842. Google Scholar Citations, ISSN(print/online): 1747-0277/1747-0285, URL/DOI: http://dx.doi.org/10.1111/j.1747-0285.2012.01408.x
  

Publications Before 2011


31)    Joshi, M., Ebalunode, J.O., Briggs, J.M. (2009). Computational insights into the interaction of the anthrax lethal factor with the N-terminal region of its substrates. Proteins: Structure, Function and Bioinformatics, 75 (2), 323-335. Google Scholar Citations, ISSN(print/online): 0887-3585/1097-0134, URL/DOI: http://dx.doi.org/10.1002/prot.22241
32)    Kulkarni-Kale, U., Bhosle, S.G., Manjari, G.S., Joshi, M., Bansode, S., Kolaskar, A.S. (2006). Curation of viral genomes: challenges, applications and the way forward. BMC Bioinformatics, 7 (5), 1-21. Google Scholar Citations, ISSN(print/online): 1471-2105, URL/DOI: http://dx.doi.org/10.1186/1471-2105-7-S5-S12