Teacher Details

Kumbhar Anupa Avinash

Department of Chemistry

anupa.kumbhar@unipune.ac.in


1)    Pokharel, Y.R., Singh, N.K., Sharma, S., Wangchuk, T., Shahi, N., Mahiya, K., Choudhary, R.K., Kumbhar, A.A., Yadav, P.N. (2025). Synthesis, characterization, and in vitro anticancer activity of a series of N(4) dimethyl isatin thiosemicarbazones and their copper(II) complexes. Journal of Molecular Structure, 1327, 141157. ISSN(print/online): 0022-2860/1872-8014, URL/DOI: http://dx.doi.org/10.1016/j.molstruc.2024.141157
2)    Badekar, P.S., Deo, H.S., Varma, M.E., Kulkarni, P.P., Maibam, A., Krishnamurty, S., Kumbhar, A.A. (2024). ‘Turning On’ to Glutathione: A Rhodamine-Based Fluorescent Chemodosimeter with Nanomolar Sensitivity. ChemistrySelect, 9 (37), e202402943 . ISSN(print/online): 2365-6549, URL/DOI: http://dx.doi.org/10.1002/slct.202402943
3)    Baraskar, M.B., Kawade, V.A., Bhat, S.S., Butcher, R.J., Mohite, M., Deshmukh, N., Kumbhar, A.A. (2022). Synthesis, Characterization and DNA Cleavage Activity of the Coordination Polymer {[Cu(phen)(azpy)(NO3)(H2O)]·(NO3)}n. Journal of Chemical Crystallography, 54 (4), 494–502. ISSN(print/online): 1074-1542/1572-8854, URL/DOI: http://dx.doi.org/10.1007/s10870-022-00923-7
4)    Kadam, S.S., Gotarne, R.P., Shinde, M.N., Mane, V.S., Khan, A.A., Kumbhar, A.A. (2022). Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes of fluorophore-anchored asymmetric thiocarbohydrazone: Synthesis, characterization and biological studies. Inorganica Chimica Acta, 536, 120887. ISSN(print/online): 0020-1693/1873-3255, URL/DOI: http://dx.doi.org/10.1016/j.ica.2022.120887
5)    Kumari, N., Bahadur, V., Butcher, R.J., Kumbhar, A.A. (2022). Synthesis, Characterization and Single Crystal X-Ray Structures of Trifluroacetylacetonate Copper(II) Complexes. Journal of Chemical Crystallography, 52 (4), 1-9. ISSN(print/online): 1074-1542/1572-8854, URL/DOI: http://dx.doi.org/10.1007/s10870-022-00937-1
6)    Yadav, P.N., Singh, N.K., Sharma, S., Krishnakumar, A., Choudhary, R.K., Kumbhar, A.A., Butcher, R.J., Pokharel, Y.R. (2022). Exploration of anticancer potency of N(4) thiomorpholinyl isatin/5-haloisatin thiosemicarbazones on coordination to Cu2+ ion. Inorganic Chemistry Communications, 143, 109767. ISSN(print/online): 1387-7003/1879-0259, URL/DOI: http://dx.doi.org/10.1016/j.inoche.2022.109767
7)    Singh, N.K., Shrestha, S., Shahi, N., Choudhary, R.K., Kumbhar, A.A., Pokharel, Y.R.A.J., Yadav, P.N. (2021). Enhancement of anticancer activity of N(4)1-(2-pyridyl)piperazinyl 5-nitroisatin thiosemicarbazone on chelation with copper(II). Asian Journal of Chemistry, 33 (3), 557-564. ISSN(print/online): 0970-7077/0975-427X, URL/DOI: http://dx.doi.org/10.14233/ajchem.2021.23004
8)    Badekar, P.S., Thakur, G.C., Varma, M.E., Ghatpande, N.S., Kulkarni, P.P., Kumbhar, A.A. (2021). Rhodamine‐Based Fluorescence ‘Turn‐On’Chemosensor: Detection of Fe3+ Ion in Aqueous Medium and MCF‐7 Live Cells. ChemistrySelect, 6 (9), 2373-2378. ISSN(print/online): 2365-6549, URL/DOI: http://dx.doi.org/10.1002/slct.202004640
9)    Kirtani, D.U., Ghatpande, N.S., Suryavanshi, K.R., Kulkarni, P.P., Kumbhar, A.A. (2021). Fluorescent Copper(II) Complexes of Asymmetric Bis(Thiosemicarbazone)s: Electrochemistry, Cellular Uptake and Antiproliferative Activity. ChemistrySelect, 6 (24), 6063-6070. ISSN(print/online): 2365-6549, URL/DOI: http://dx.doi.org/10.1002/slct.202101663
10)    Shaikh, S., Bhat, S.S., Revankar, V.K., Hedge, P.L., Kate, A.N., Kirtani, D.U., Kumbhar, A., Kumbar, V., Bhat, K. (2021). Synthesis, structural characterization, protein binding, DNA cleavage and anticancer activity of fluorophore labelled copper(II) complexes based on 1,8-naphthalimide conjugates. New Journal of Chemistry, 45 (35), 16319-16332. ISSN(print/online): 1144-0546/1369-9261, URL/DOI: http://dx.doi.org/10.1039/D1NJ02696H
11)    Singh, N.K., Shrestha, S., Shahi, N., Choudhary, R.K., Kumbhar, A.A., Pokharel, Y.R., Yadav, P.N. (2021). Anticancer Potential of N(4)Substituted 5-Nitroisatin Thiosemicarbazones and Their Copper(Ii) Complexes. Rasayan Journal of Chemistry, 14 (3), 1600-1610. ISSN(print/online): 0974-1496/0976-0083, URL/DOI: http://dx.doi.org/10.31788/RJC.2021.1436341
12)    Pawar, S., Amate, A., Chakravarty, D., Butcher, R. J., Kumbhar, A. A. (2021). Cu(II) complexes of 2-indole thiocarbohydrazones: synthesis, characterization and DNA cleavage studies. Journal of Chemical Sciences, 133 (4), 107. ISSN(print/online): 0974-3626/0973-7103 , URL/DOI: http://dx.doi.org/10.1007/s12039-021-01962-x
13)    Bhattarai, N., Kumbhar, A.A., Pokharel, Y.R., Yadav, P.N. (2021). Anticancer Potential of Coumarin and its Derivatives. Mini Reviews in Medicinal Chemistry, 21 (19), 2996-3029. Google Scholar Citations, ISSN(print/online): 1389-5575/1875-5607 , URL/DOI: http://dx.doi.org/10.2174/1389557521666210405160323
14)    Singh, N.K., Kumbhar, A.A., Pokharel, Y.R., Yadav, P.N. (2020). Anticancer potency of copper(II) complexes of thiosemicarbazones. Journal of Inorganic Biochemistry, 210 (9), 111134. Google Scholar Citations, ISSN(print/online): 0162-0134/1873-3344, URL/DOI: http://dx.doi.org/10.1016/j.jinorgbio.2020.111134
15)    Kulkarni, P.A., More, M.A., Nandre, V., Kumbhar, A. (2020). Investigations on sensing of picric acid in aqueous medium via fluorescence quenching of quinine sulfate. Modern Physics Letters B, 34 (7), 2040040. ISSN(print/online): 0217-9849/1793-6640, URL/DOI: http://dx.doi.org/10.1142/S0217984920400400
16)    Shinde, M.N., Rao, S.S., Gejji, S.P., Kumbhar, A.A. (2018). Distinct Photophysical Behaviour and Transport of Cell-Impermeable [Ru (bpy) 2dppz] 2+ in Live Cells using Cucurbit [7] uril as Delivery System. Dalton Transactions, 47 (11), 3857-3863. ISSN(print/online): 1477-9226/1477-9234, URL/DOI: http://dx.doi.org/10.1039/c7dt04230b
17)    Badekar, P.S., Kumbhar, A.A. (2018). Anthracene-based fluorescence turn-on chemodosimeter for the recognition of persulfate anion. New Journal of Chemistry, 42 (5), 3917-3923. ISSN(print/online): 1144-0546/1369-9261, URL/DOI: http://dx.doi.org/10.1039/c7nj03425c
18)    Rajebhosale, B.S., Dongre, S.N., Deshpande, S.S., Kate, A.N., Kumbhar, A.A., (2017). Aryl-1H-imidazole[4,5f][1,10]phenanthroline Cu(II) complexes: Electrochemical and DNA interaction studies. Journal of Inorganic Biochemistry, 175, 129-137. ISSN(print/online): 0162-0134/1873-3344, URL/DOI: http://dx.doi.org/10.1016/j.jinorgbio.2017.07.008
19)    Ranade, D.S., Shravage, B.V., Kumbhar, A.A., Sonawane, U.B., Jani, V.P., Joshi, R.R., Kulkarni, P.P. (2017). Thiosemicarbazone Moiety Assist in Interaction of Planar Aromatic Molecules with Amyloid Beta Peptide and Acetylcholinesterase. ChemistrySelect, 2 (13), 3911-3916. ISSN(print/online): 2365-6549, URL/DOI: http://dx.doi.org/10.1002/slct.201700588
20)    Sontakke, V.A., Lawande, P.P., Kate, A.N., Khan, A., Joshi, R., Kumbhar, A.A., Shinde, V.S. (2016). Antiproliferative activity of bicyclic benzimidazole nucleosides: synthesis, DNA-binding and cell cycle analysis. Organic and Biomolecular Chemistry, 14 (17), 4136-4145. Google Scholar Citations, ISSN(print/online): 1477-0520/1477-0539, URL/DOI: http://dx.doi.org/10.1039/C6OB00527F
21)    Abosede, O.O., Vyas, N.A., Singh, S.B., Kumbhar, A.S., Kate, A., Kumbhar, A.A., Khan, A., Erxleben, A., Smith, P., de Kock, C., Hoffmann, F. (2016). Copper (ii) mixed-ligand polypyridyl complexes with doxycycline–structures and biological evaluation. Dalton Transactions, 45 (7), 3003-3012. Google Scholar Citations, ISSN(print/online): 1477-9226/1477-9234, URL/DOI: http://dx.doi.org/10.1039/c5dt04405g
22)    Rane, L.B., Kate, A.N., Ramteke, S.N., Shravage, B.V., Kulkarni, P.P., Kumbhar, A.A. (2016). Fluorescent zinc(II) complexes for gene delivery and simultaneous monitoring of protein expression. Dalton Transactions, 45 (42), 16984-16996. ISSN(print/online): 1477-9226/1477-9234, URL/DOI: http://dx.doi.org/10.1039/c6dt02871c
23)    Richter, S., Singh, S., Draca, D., Kate, A., Kumbhar, A., Kumbhar, A.S., Maksimovic-Ivanic, D., Mijatovic, S., Lönnecke, P., Hey-Hawkins, E. (2016). Antiproliferative activity of ruthenium (ii) arene complexes with mono-and bidentate pyridine-based ligands. Dalton Transactions, 45 (33), 13114-13125. Google Scholar Citations, ISSN(print/online): 1477-9226/1477-9234, URL/DOI: http://dx.doi.org/10.1039/c6dt01782g
24)    Sontakke, V.A., Kate, A.N., Ghosh, S., More, P., Gonnade, R., Kumbhar, N.M., Kumbhar, A.A., Chopade, B.A., Shinde, V.S. (2015). Synthesis, DNA interaction and anticancer activity of 2-anthryl substituted benzimidazole derivatives. New Journal of Chemistry, 39 (6), 4882-4890. Google Scholar Citations, ISSN(print/online): 1144-0546/1369-9261, URL/DOI: http://dx.doi.org/10.1039/C4NJ02415J
25)    Ingle, S.A., Kate, A.N., Kumbhar, A.A., Khan, A.A., Rao, S.S., Gejji, S.P. (2015). Synthesis and biological evaluation of copper (II) pyrenethiosemicarbazone. RSC Advances, 5 (59), 47476-47487. Google Scholar Citations, ISSN(print/online): 2046-2069, URL/DOI: http://dx.doi.org/10.1039/C5RA00020C
26)    Kate, A.N., Kumbhar, A.A., Khan, A.A., Joshi, P.V., Puranik, V.G. (2014). Monitoring cellular uptake and cytotoxicity of copper (ii) complex using a fluorescent anthracene thiosemicarbazone ligand. Bioconjugate Chemistry, 25 (1), 102-114. Google Scholar Citations, ISSN(print/online): 1043-1802/1520-4812, URL/DOI: http://dx.doi.org/10.1021/bc400385d
27)    Kumbhar, A.A., Franks, A.T., Butcher, R.J., Franz, K.J. (2013). Light uncages a copper complex to induce nonapoptotic cell death. Chemical Communications, 49, 2460-2462. Google Scholar Citations, ISSN(print/online): 1359-7345/1364-548X, URL/DOI: http://dx.doi.org/10.1039/C3CC38927H
28)    Kawade, V., Kumbhar, A., Sapre, A., Kumbhar, A. (2013). Photophysical properties of 3-(9-anthrylmethyl) pentane-2, 4-dione. Chemical Physics Letters, 583, 198-202. ISSN(print/online): 0009-2614/1873-4448, URL/DOI: http://dx.doi.org/10.1016/j.cplett.2013.07.071
29)    Kate, A.N., Kumbhar, A.A., Sapre, A.V., Peerannawar, S.R., Gejji, S.P. (2013). Interaction of a Hydrated Electron with Anthracenethiosemicarbazone: A Pulse Radiolysis Study. Journal of Physical Chemistry A, 117 (26), 5447-5453. Google Scholar Citations, ISSN(print/online): 1089-5639/1520-5215, URL/DOI: http://dx.doi.org/10.1021/jp402202s
31)    Ezadyar, S.A., Kumbhar, A.S., Kumbhar, A.A., Khan, A. (2012). Binuclear ruthenium(II) polypyridyl complexes: DNA cleavage and mitochondria mediated apoptosis induction. Polyhedron, 36 (1), 45-55. Google Scholar Citations, ISSN(print/online): 0277-5387/1873-3719, URL/DOI: http://dx.doi.org/10.1016/j.poly.2012.01.024
32)    Bhat, S.S., Kumbhar, A.S., Kumbhar, A.A., Khan, A. (2012). Efficient DNA Condensation Induced by Ruthenium(II) Complexes of a Bipyridine-Functionalized Molecular Clip Ligand. Chemistry-A European Journal, 18 (51), 16383-16392. Google Scholar Citations, ISSN(print/online): 0947-6539/1521-3765, URL/DOI: http://dx.doi.org/10.1002/chem.201200407
33)    Kawade, V.A., Kumbhar, A.A., Kumbhar, A.S., Näther, C., Erxleben, A., Sonawane, U.B., Joshi, R.R. (2011). Mixed ligand cobalt(II) picolinate complexes: synthesis, characterization, DNA binding and photocleavage. Dalton Transactions, 40 (3), 639-650. Google Scholar Citations, ISSN(print/online): 1477-9226/1477-9234, URL/DOI: http://dx.doi.org/10.1039/C0DT01078B
34)    Bhat, S.S., Kumbhar, A.S., Kumbhar, A.A., Khan, A., Lönnecke, P., Hey-Hawkins, E. (2011). Ruthenium(II) polypyridyl complexes as carriers for DNA delivery. Chemical Communications, 47 (39), 11068-11070. Google Scholar Citations, ISSN(print/online): 1359-7345/1364-548X, URL/DOI: http://dx.doi.org/10.1039/C1CC13863D
35)    Bhat, S.S., Kumbhar, A.A., Heptullah, H., Khan, A.A., Gobre, V.V., Gejji, S.P., Puranik, V.G. (2011). Synthesis, electronic structure, DNA and protein binding, DNA cleavage, and anticancer activity of fluorophore-labeled copper (II) complexes. Inorganic Chemistry, 50 (2), 545-558. Google Scholar Citations, ISSN(print/online): 0020-1669/1520-510X, URL/DOI: http://dx.doi.org/10.1021/ic101534n
  

Publications Before 2011


36)    Islam, M.N., Kumbhar, A.A., Kumbhar, A.S., Zeller, M., Butcher, R.J., Dusane, M.B., Joshi, B.N. (2010). Bis(maltolato)vanadium(III)-Polypyridyl Complexes: Synthesis, Characterization, DNA Cleavage, and Insulin Mimetic Activity. Inorganic Chemistry, 49 (18), 8237-8246. Google Scholar Citations, ISSN(print/online): 0020-1669/1520-510X, URL/DOI: http://dx.doi.org/10.1021/ic9025359
37)    Deshpande, M.S., Kumbhar, A.A., Kumbhar, A.S., Kumbhakar, M., Pal, H., Sonawane, U.B., Joshi, R.R. (2009). Ruthenium(II) Complexes of Bipyridine−Glycoluril and their Interactions with DNA. Bioconjugate Chemistry, 20 (3), 447-459. Google Scholar Citations, ISSN(print/online): 1043-1802/1520-4812, URL/DOI: http://dx.doi.org/10.1021/bc800298t
38)    Kumbhar, A.A., Kumbhar, A.S., Puranik, V.G. (2008). An Unexpected Metal-Promoted Transformation Yields An Anthrylmethyl Spiroanthracene. The Journal of Organic Chemistry, 73 (9), 3559-3561. ISSN(print/online): 0022-3263/1520-6904, URL/DOI: http://dx.doi.org/10.1021/jo702284t
39)    Deshpande, M.S., Kumbhar, A.A., Kumbhar, A.S. (2007). Hydrolytic Cleavage of DNA by a Ruthenium(II) Polypyridyl Complex. Inorganic Chemistry, 46 (14), 5450-5452. Google Scholar Citations, ISSN(print/online): 0020-1669/1520-510X, URL/DOI: http://dx.doi.org/10.1021/ic070331d
40)    Ghosh, S., Barve, A.C., Kumbhar, A.A., Kumbhar, A.S., Puranik, V.G., Datar, P.A., Sonawane, U.B., Joshi, R.R. (2006). Synthesis, characterization, X-ray structure and DNA photocleavage by cis-dichloro bis (diimine) Co (III) complexes. Journal of Inorganic Biochemistry, 100 (3), 331-343. Google Scholar Citations, ISSN(print/online): 0162-0134/1873-3344, URL/DOI: http://dx.doi.org/10.1016/j.jinorgbio.2005.11.022
41)    Barve, A.C., Ghosh, S., Kumbhar, A.A., Kumbhar, A.S., Puranik, V.G. (2005). DNA-binding studies of mixed ligand cobalt(III) complexes. Transition Metal Chemistry, 30 (3), 312-316. Google Scholar Citations, ISSN(print/online): 0340-4285/1572-901X, URL/DOI: http://dx.doi.org/10.1007/s11243-004-5855-0
42)    Murugkar, A., Padhye, S., Vorobjeva, L. (2003). Pre-formed iron-thiosemicarbazone chelates as ribonucleotide reductase inhibitors. Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 42 (8), 1861-1864. Google Scholar Citations, ISSN(print/online): 0376-4710/0975-0975, URL/DOI: http://nopr.niscair.res.in/bitstream/123456789/20708/1/IJCA%2042A%288%29%201861-1864.pdf
43)    Murugkar, A., Karve, M., Padhye, S., Narayanaswamy, R. (2002). Immobilization of dithiooxamide in biopolymer and synthetic films for possible use in optical fibre copper probe. Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 41 (7), 1397-1401. ISSN(print/online): 0376-4710/0975-0975, URL/DOI: http://nopr.niscair.res.in/bitstream/123456789/18311/1/IJCA%2041A%287%29%201397-1401.pdf
44)    Dutta, S., Murugkar, A., Gandhe, N., Padhye, S. (2001). Enhanced Antioxidant Activities of Metal Conjugates of Curcumin Derivatives. Metal-Based Drugs, 8 (4), 183-188. Google Scholar Citations, ISSN(print/online): 0793-0291/1687-5486, URL/DOI: http://dx.doi.org/10.1155/MBD.2001.183
45)    Murugkar, A., Padhye, S., Guha-Roy, S., Wagh, U. (1999). Metal complexes of Taxol precursor: 1. Synthesis, characterization and antitumor activity of the copper complex of 10-deacetylbaccatin thiosemicarbazone. Inorganic Chemistry Communications, 2 (11), 545-548. Google Scholar Citations, ISSN(print/online): 1387-7003/1879-0259, URL/DOI: http://dx.doi.org/10.1016/S1387-7003(99)00152-5
46)    Murugkar, A., Unnikrishnan, B., Padhye, S., Bhonde, R., Teat, S., Triantafillou, E., Sinn, E. (1999). Hormone anchored metal complexes 1. Synthesis, structure, spectroscopy and in vitro antitumor activity of testosterone acetate thiosemicarbazone and its metal complexes . Metal-Based Drugs, 6 (3), 177-182. Google Scholar Citations, ISSN(print/online): 0793-0291/1687-5486, URL/DOI: http://dx.doi.org/10.1155/MBD.1999.177
47)    Murugkar, A., Padhye, S., Deobagkar, D. (1999). Synthesis, spectroscopy and electrochemistry Fe(II) and Fe(III) quinonemonooxime complexes and DNA cleaving activities . Metal-Based Drugs, 6 (2), 81-85. ISSN(print/online): 0793-0291/1687-5486, URL/DOI: http://dx.doi.org/10.1155/MBD.1999.81
48)    Murugkar, A., Bemire, R., Padhye, S., Groy, T. (1999). X-ray crystal structure of the cytotoxic planar Ni (II) complex of -dimethy 2-acety pyridine thiosemicarbazone. Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 38 (10), 981-984. Google Scholar Citations, ISSN(print/online): 0376-4710/0975-0975, URL/DOI: http://nopr.niscair.res.in/bitstream/123456789/15939/1/IJCA%2038A%2810%29%20981-984.pdf
49)    Murugkar, A., Bendre, R., Kumbhar, A., Padhye, S., Pritchard, R., McAuliffe, C.A. (1999). Crystal structure of cationic complex of 2[Co-III(APOTSC)(2)](+)[(CoCl4)-Cl-II](2-). Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 38 (10), 977-980. ISSN(print/online): 0376-4710/0975-0975, URL/DOI: http://nopr.niscair.res.in/bitstream/123456789/16025/1/IJCA%2038A%2810%29%20977-980.pdf
50)    Bendre, R., Murugkar, A., Padhye, S., Kulkarni, P., Karve, M. (1998). Synthesis and characterization of coordinatively unsaturated copper (II) complexes of 1,3-bis(2′-pyridyl)-1,2-diaza-2-butene and their antityrosinase activity . Metal-Based Drugs, 5 (2), 59-66. Google Scholar Citations, ISSN(print/online): 0793-0291/1687-5486, URL/DOI: http://dx.doi.org/10.1155/MBD.1998.59
51)    Ratnasamy, C., Murugkar, A., Padhye, S., Pardy, S. (1996). Zeolite-encapsulated Cu(II)-salen complex as a catalyst for oxidation of cyclohexanol . Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 35 (1), 1-3. Google Scholar Citations, ISSN(print/online): 0376-4710/0975-0975.
52)    Padhye, S., Murugkar, A., Yerande, R., Chikate, R. (1996). Properties of linearbis-dinuclear complexes afforded by schiff base ligands containing catechol and imidazole group. Journal of Chemical Sciences, 108 (3), 264. ISSN(print/online): 0974-3626/0973-7103 , URL/DOI: http://dx.doi.org/10.1007/BF02870032