Teacher Details
Rohan Janardhan Meshram
Bioinformatics Centre
rohan_meshram@rediffmail.com
Research Areas : Computer Aided Drug Discovery, Medicinal Chemistry, Chemoinformatics
| 1) | Joshi, R., Gaikwad, H., Soge, B., Alshammari, A., Albekairi, N.A., Kabra, A., Yashwante, U., Kolte, B., Lokhande, P., Meshram, R.J. (2025). Exploring pyrazolines as potential inhibitors of NSP3-macrodomain of SARS-CoV-2: synthesis and in silico analysis. Scientific Reports,
15 (1), 767.
ISSN(print/online): 2045-2322,
URL/DOI: http://dx.doi.org/10.1038/s41598-024-81711-5
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| 2) | Shaikh, S.A., Pachorkar, P.Y., Meshram, R.J., Boraste, D.R., More, R.A., Chobe, S.S., Ballabh, D., Wakchaure, S.N., Labhade, S.R., Kale, R.R., Labhade, H.S. (2024). Synthesis, Biological and Molecular Docking Studies of Thiazole-Thiadiazole derivatives as potential Anti-Tuberculosis Agents. Chemistry and Biodiversity,
21 (6), e202400496.
ISSN(print/online): 1612-1872/1612-1880,
URL/DOI: http://dx.doi.org/10.1002/cbdv.202400496
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| 3) | Shaikh, S.A., Labhade, S.R., Kale, R.R., Pachorkar, P.Y., Meshram, R.J., Jain, K.S., Labhade, H.S., Bhanushali, D.D., More, R.A., Nerkar, C.K., Chobe, S.S. (2024). Thiadiazole-thiazole derivatives as potent anti-tubercular agents: Synthesis, biological evaluation, and In silico docking studies. European Journal of Medicinal Chemistry Reports,
12, 100183.
ISSN(print/online): 2772-4174,
URL/DOI: http://dx.doi.org/10.1016/j.ejmcr.2024.100183
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| 4) | Dahiwade, M., Vyawahare, N., Garade, P., Marathe, A., Meshram, R., Suryawanshi, M., Palake, A., Kodam, K., Ottoor, D. (2024). Biological activity and biomolecule interaction of pyridyl thiazole derivative and its copper complex. Journal of Molecular Liquids,
404, 124936.
ISSN(print/online): 0167-7322/1873-3166,
URL/DOI: http://dx.doi.org/10.1016/j.molliq.2024.124936
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| 5) | Meshram, R., Kolte, B., Gacche, R. (2024). Reverse vaccinology approach for identification of epitopes from E1 protein as peptide vaccine against HCV: A proof of concept. Vaccine,
42 (24), 1-13.
ISSN(print/online): 0264-410X/1873-2518,
URL/DOI: http://dx.doi.org/10.1016/j.vaccine.2024.07.007
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| 6) | Vane, V., Mokal, R., Yashwante, U., Meshram, R. J., Jadhava, S. (2024). Synthesis and In-Vitro/Silico Evaluation of Fluorinated Chalcones. Oriental Journal of Chemistry,
40 (4), 1077-1086.
ISSN(print/online): 0970-020X/2231-5039,
URL/DOI: http://dx.doi.org/10.13005/ojc/400419
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| 7) | Hublikar, M., Kadu, V., Edake, N., Raut, D., Shirame, S., Z. Ahmed, M., Makam, P., Ahmad, M.S., Meshram, R.J., Bhosale, R. (2024). Design, Synthesis, Anti-Cancer, Anti-inflammatory and In Silico Studies of 3-Substituted-2-Oxindole Derivatives. Chemistry and Biodiversity,
21 (11), e202400844.
ISSN(print/online): 1612-1872/1612-1880,
URL/DOI: http://dx.doi.org/10.1002/cbdv.202400844
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| 8) | Ballabh, D., Shaikh, S., More, R.A., Meshram, R.J. (2024). Dynamics, mechanistic and energetic evaluation of thiazole-thiadiazole compounds in flavin dependent thymidylate synthase of Mycobacterium tuberculosis. International Journal of Biological Macromolecules,
289, 138839.
ISSN(print/online): 0141-8130/1879-0003,
URL/DOI: http://dx.doi.org/10.1016/j.ijbiomac.2024.138839
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| 9) | Lodha, K., Wavhal, D., Bhujbal, N., Mazire, P., Bhujbal, S., Korde, A., Bagul, K., Roy, A., Meshram, R., Shinde, V. (2023). Synthesis and biological evaluation of 9-aryl-1,8-dioxo-octahydroxanthene derivatives as antileishmanial agents. Results in Chemistry,
5, 100943.
ISSN(print/online): 2211-7156,
URL/DOI: http://dx.doi.org/10.1016/j.rechem.2023.100943
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| 10) | Patil, A.M., Lagad, P.M., Soge, B., Meshram, R., Lokhande, M.N., Lokhande, P.D. (2023). Ammonium chloride mediated synthesis of 2-aryl-phthalazinone from O-formyl benzoic acid and in silico applications. ARKIVOC,
2023 (7), 1-11.
ISSN(print/online): 1551-7004/1551-7012,
URL/DOI: http://dx.doi.org/10.24820/ark.5550190.p011.972
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| 11) | More, N.A., Jadhao, N.L., Meshram, R.J., Tambe, P., Salve, R.A., Sabane, J.K., Sawant, S.N., Gajbhiye, V., Gajbhiye, J.M. (2022). Novel 3-fluoro-4-morpholinoaniline derivatives: Synthesis and assessment of anti-cancer activity in breast cancer cells. Journal of Molecular Structure,
1253, 132127.
ISSN(print/online): 0022-2860/1872-8014,
URL/DOI: http://dx.doi.org/10.1016/j.molstruc.2021.132127
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| 12) | Lodha, K.K., Wavhal, D.S., Bhalekar, S.B., Meshram, R.J., Shinde, V.S. (2022). Exploring New Tetrahydrothienopyridine Derivatives as Platelet Agglutination Inhibitors: Synthesis, Biological Evaluation and In Silico Study. ChemistrySelect,
7 (2), 202103428.
ISSN(print/online): 2365-6549,
URL/DOI: http://dx.doi.org/10.1002/slct.202103428
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| 13) | Meshram, R.J., Kathwate, G.H., Gacche, R.N. (2022). Progress, evolving therapeutic/diagnostic approaches, and challenges in the management of hepatitis C virus infections. Archives of Virology,
167, 717-736.
ISSN(print/online): 0304-8608/1432-8798,
URL/DOI: http://dx.doi.org/10.1007/s00705-022-05375-0
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| 14) | Meshram, R.J., Bagul, K.T., Aouti, S.U., Shirsath, A.M., Duggal, H., Gacche, R.N. (2021). Modeling and simulation study to identify threonine synthase as possible drug target in Leishmania major. Molecular Diversity,
25, 1679-1700.
ISSN(print/online): 1381-1991/1573-501X,
URL/DOI: http://dx.doi.org/10.1007/s11030-020-10129-8
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| 15) | Sharbidre, A., Dhage, P., Duggal, H., Meshram, R. (2021). In silico Investigation of Tridax procumbens Phyto-Constituents Against SARS-CoV-2 Infection. Biointerface Research in Applied Chemistry,
11 (4), 12120-12148.
ISSN(print/online): 2069-5837,
URL/DOI: http://dx.doi.org/10.33263/BRIAC114.1212012148
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| 16) | Sawant, A.S., Kamble, S.S., Pisal, P.M., Sawant, S.S., Hese, S.V., Bagul, K.T., Pinjari, R.V., Kamble, V.T., Meshram, R.J., Gacche, R.N. (2021). Synthesis and evaluation of N-(4-(substituted)-3-(trifluoromethyl) phenyl) isobutyramides and their N-ethyl analogous as anticancer, anti-angiogenic & antioxidant agents: In vitro and in silico analysis. Computational Biology and Chemistry,
92, 107484.
ISSN(print/online): 1476-9271/1476-928X,
URL/DOI: http://dx.doi.org/10.1016/j.compbiolchem.2021.107484
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| 17) | Meshram, R.J., Bagul, K.T., Pawnikar, S.P., Barage, S.H., Kolte, B.S., Gacche, R.N. (2020). Known compounds and new lessons: structural and electronic basis of flavonoid-based bioactivities. Journal of Biomolecular Structure and Dynamics,
38 (4), 1168-1184. Google Scholar Citations,
ISSN(print/online): 0739-1102/1538-0254,
URL/DOI: http://dx.doi.org/10.1080/07391102.2019.1597770
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| 18) | Meshram, R.J., Shirsath, A., Aouti, S., Bagul, K., Gacche, R.N. (2020). Molecular modeling and simulation study of homoserine kinase as an effective leishmanial drug target. Journal of Molecular Modeling,
26 (8), 218.
ISSN(print/online): 1610-2940/0948-5023,
URL/DOI: http://dx.doi.org/10.1007/s00894-020-04473-7
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| 19) | Patil, A., Duggal, H., Bagul, K.T., Kamble, S., Lokhande, P., Gacche, R., Meshram, R. (2020). Synthesis of new 3-arylaminophthalides and 3-indolyl-phthalides using ammonium chloride, evaluation of their anti-mycobacterial potential and docking study. Combinatorial Chemistry and High Throughput Screening,
23 (8), 723-739. Google Scholar Citations,
ISSN(print/online): 1386-2073/1875-5402,
URL/DOI: http://dx.doi.org/10.2174/1386207323666200422082754
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| 20) | Sawant, A.S., Kamble, S.S., Pisal, P.M., Meshram, R.J., Sawant, S.S., Kamble, V.A., Kamble, V.T., Gacche, R.N. (2020). Synthesis and evaluation of a novel series of 6-bromo-1-cyclopentyl-1H-indazole-4-carboxylic acid-substituted amide derivatives as anticancer, antiangiogenic, and antioxidant agents. Medicinal Chemistry Research,
29 (1), 17-32.
ISSN(print/online): 1054-2523/1554-8120,
URL/DOI: http://dx.doi.org/10.1007/s00044-019-02454-x
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| 21) | Hartung, F., Patil, A., Meshram, R.J., Weber, G.F. (2020). Gene expression signatures of site-specificity in cancer metastases. Clinical and Experimental Metastasis,
37 (1), 159-171. Google Scholar Citations,
ISSN(print/online): 0262-0898/1573-7276,
URL/DOI: http://dx.doi.org/10.1007/s10585-019-09995-w
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| 22) | Meshram, R.J., Goundge, M.B., Kolte, B.S., Gacche, R.N. (2019). An in silico approach in identification of drug targets in Leishmania: A subtractive genomic and metabolic simulation analysis. Parasitology International,
69, 59-70.
ISSN(print/online): 1383-5769/1873-0329,
URL/DOI: http://dx.doi.org/10.1016/j.parint.2018.11.006
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| 23) | Ambhore, A.N., Kamble, S.S., Kadam, S.N., Kamble, R.D., Hebade, M.J., Hese, S.V., Gaikwad, M.V., Meshram, R.J., Gacche, R.N., Dawane, B.S. (2019). Design, synthesis and in silico study of pyridine based 1, 3, 4-oxadiazole embedded hydrazinecarbothioamide derivatives as potent anti-tubercular agent. Computational Biology and Chemistry,
80, 54-65.
ISSN(print/online): 1476-9271/1476-928X,
URL/DOI: http://dx.doi.org/10.1016/j.compbiolchem.2019.03.002
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| 24) | Kolte, B.S., Londhe, S.R., Bagul, K.T., Pawnikar, S.P., Goundge, M.B., Gacche, R.N., Meshram, R.J. (2019). FlavoDb: a web-based chemical repository of flavonoid compounds. 3 Biotech,
9 (11), 431.
ISSN(print/online): 2190-572X/2190-5738,
URL/DOI: http://dx.doi.org/10.1007/s13205-019-1962-7
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| 25) | Shaikh, R.U., Meshram, R.J., Gacche, R.N. (2019). An investigation on in vitro anti-inflammatory and antiproliferative potential of isolated Labdane diterpenoids from Andrographis paniculata (Burm. f.) wall. Ex nees: An important medicinal plant prescribed in Ayurveda. European Journal of Integrative Medicine,
32, 100983.
ISSN(print/online): 1876-3820/1876-3839,
URL/DOI: http://dx.doi.org/10.1016/j.eujim.2019.100983
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| 26) | Patil, K.K., Meshram, R.J., Barage, S.H., Gacche, R.N. (2019). Dietary flavonoids inhibit the glycation of lens proteins: implications in the management of diabetic cataract. 3 Biotech,
9 (2), 47.
ISSN(print/online): 2190-572X/2190-5738,
URL/DOI: http://dx.doi.org/10.1007/s13205-019-1581-3
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| 27) | Kolte, B.S., Londhe, S.R., Solanki, B.R., Gacche, R.N., Meshram, R.J. (2018). FilTer BaSe: A web accessible chemical database for small compound libraries. Journal of Molecular Graphics and Modelling,
80, 95-103.
ISSN(print/online): 1093-3263/1873-4243,
URL/DOI: http://dx.doi.org/10.1016/j.jmgm.2017.12.020
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| 28) | Meshram, R.J., Dangre, A.M., Gacche, R.N. (2018). In silico Modeling and Drug Interaction Analysis of Molecular Structure of Ecto-Domain of E1 Glycoprotein of HCV. International Journal of Proteomics and Bioinformatics,
3 (1), 1-6.
ISSN(print/online): 2687-9719,
URL/DOI: https://www.scireslit.com/Proteomics/IJPB-ID18.pdf
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| 29) | Meshram, R.J., Baladhye, V.B., Gacche, R.N., Karale, B.K., Gaikar, R.B. (2017). Pharmacophore mapping approach for drug target identification: A chemical synthesis and in silico study on novel thiadiazole compounds. Journal of Clinical and Diagnostic Research,
11 (5), KF01-KF08. Google Scholar Citations,
ISSN(print/online): 2249-782X/0973-709X,
URL/DOI: http://dx.doi.org/10.7860/JCDR/2017/22761.9925
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| 30) | Hese, S.V., Meshram, R.J., Kamble, R.D., Mogle, P.P., Patil, K.K., Kamble, S.S., Gacche, R.N., Dawane, B.S. (2017). Antidiabetic and allied biochemical roles of new chromeno-pyrano pyrimidine compounds: synthesis, in vitro and in silico analysis. Medicinal Chemistry Research,
26 (4), 805-818. Google Scholar Citations,
ISSN(print/online): 1054-2523/1554-8120,
URL/DOI: http://dx.doi.org/10.1007/s00044-017-1794-0
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| 31) | Mogle, P.P., Meshram, R.J., Hese, S.V., Kamble, R.D., Kamble, S.S., Gacche, R.N., Dawane, B.S. (2016). Synthesis and molecular docking studies of a new series of bipyrazol-yl-thiazol-ylidene-hydrazinecarbothioamide derivatives as potential antitubercular agents. MedChemComm,
7 (7), 1405–1420. Google Scholar Citations,
ISSN(print/online): 2040-2503/2040-2511,
URL/DOI: http://dx.doi.org/10.1039/c6md00085a
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| 32) | Gacche, R.N., Meshram, R.J., Shegokar, H.D., Gond, D.S., Kamble, S.S., Dhabadge, V.N., Utage, B.G., Patil, K.K., More, R.A. (2015). Flavonoids as a scaffold for development of novel anti-angiogenic agents: An experimental and computational enquiry. Archives of Biochemistry and Biophysics,
577, 35-48. Google Scholar Citations,
ISSN(print/online): 0003-9861/1096-0384,
URL/DOI: http://dx.doi.org/10.1016/j.abb.2015.04.009
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| 33) | Kamble, R.D., Hese, S.V., Meshram, R.J., Kote, J.R., Gacche, R.N., Dawane, B.S. (2015). Green synthesis and in silico investigation of dihydro-2H-benzo[1,3]oxazine derivatives as inhibitors of Mycobacterium tuberculosis. Medicinal Chemistry Research,
24 (3), 1077-1088. Google Scholar Citations,
ISSN(print/online): 1054-2523/1554-8120,
URL/DOI: http://dx.doi.org/10.1007/s00044-014-1165-z
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| 34) | Gacche, R.N., Shegokar, H.D., Gond, D.S., Meshram, R.J. (2014). Structural peculiarities of flavonoids influence anti-angiogenic, cytotoxic and antioxidant effects: experimental and insilico analysis. Cancer Research,
74 (19), 1006-1006. Google Scholar Citations,
ISSN(print/online): 0008-5472/1538-7445,
URL/DOI: http://dx.doi.org/10.1158/1538-7445.AM2014-1006
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| 35) | Kadam, A., Dawane, B., Pawar, M., Shegokar, H., Patil, K., Meshram, R., Gacche, R. (2014). Development of novel pyrazolone derivatives as inhibitors of aldose reductase: An eco-friendly one-pot synthesis, experimental screening and in silico analysis. Bioorganic Chemistry,
53, 67-74. Google Scholar Citations,
ISSN(print/online): 0045-2068/1090-2120,
URL/DOI: http://dx.doi.org/10.1016/j.bioorg.2014.02.002
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| 36) | Gacche, R.N., Meshram, R.J. (2013). Targeting tumor micro-environment for design and development of novel anti-angiogenic agents arresting tumor growth. Progress in Biophysics and Molecular Biology,
113 (2), 333-354. Google Scholar Citations,
ISSN(print/online): 0079-6107/1873-1732,
URL/DOI: http://dx.doi.org/10.1016/j.pbiomolbio.2013.10.001
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| 37) | Jadhav, S.G., Meshram, R.J., Gond, D.S., Gacche, R.N. (2013). Inhibition of growth of Helicobacter pylori and its urease by coumarin derivatives: Molecular docking analysis. Journal of Pharmacy Research,
7 (8), 705-711. Google Scholar Citations,
ISSN(print/online): 0974-6943,
URL/DOI: http://dx.doi.org/10.1016/j.jopr.2013.09.002
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| 38) | Bandgar, B.P., Adsul, L.K., Chavan, H.V., Jalde, S.S., Shringare, S.N., Shaikh, R., Meshram, R.J., Gacche, R.N., Masand, V. (2012). Synthesis, biological evaluation, and docking studies of 3-(substituted)-aryl-5-(9-methyl-3-carbazole)-1H-2-pyrazolines as potent anti-inflammatory and antioxidant agents. Bioorganic and Medicinal Chemistry Letters,
22 (18), 5839-5844. Google Scholar Citations,
ISSN(print/online): 0960-894X/1464-3405,
URL/DOI: http://dx.doi.org/10.1016/j.bmcl.2012.07.080
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| 39) | Meshram, R.J., Vikhe, P.P., Gavhane, A.J., Jangle, S.N., Gacche, R.N. (2012). Modeling and molecular dynamics studies on ESP1 and ESP6 epitopes of early secreted antigenic target protein ESAT-6 from Mycobacterium tuberculosis. Pharmacophore,
3 (4), 209-216.
ISSN(print/online): 2229-5402,
URL/DOI: https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.734.7443&rep=rep1&type=pdf
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| 40) | Vikhe, P.P., Gaikar, R.B., Vikhe, G.P., Meshram, R.J., Karale, B.K. (2011). Molecular Properties and Docking Studies on Chromone Pyrazolones as Potential Inhibitors of P38 Map Kinase. International Journal of Pharmacy and Pharmaceutical Sciences,
3 (5), 321-324. Google Scholar Citations,
ISSN(print/online): 2656-0097/0975-1491,
URL/DOI: https://www.researchgate.net/profile/Dr-Rohan-Meshram/publication/258878549_Molecular_properties_and_docking_studies_on_chromone_pyrazolones_as_potential_inhibitors_of_p38_MAP_kinase/links/0c9605294e07d3dfa3000000/Molecular-properties-and-docking-studies-on-chromone-pyrazolones-as-potential-inhibitors-of-p38-MAP-kinase.pdf
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| 41) | Meshram, R.J., Jangle, S.N. (2011). Comparative metabolomic investigation of Leishmania major and homo sapiens: An in-silico technique to discover and develop novel drug targets. Pharmacophore,
2 (2), 98-107. Google Scholar Citations,
ISSN(print/online): 2229-5402,
URL/DOI: https://pharmacophorejournal.com/article/comparative-metabolomic-investigation-of-leishmania-major-and-homosapiens-an-in-silico-technique-to-discover-and-develop-novel-drug-targets
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